Showing posts with label research. Show all posts
Showing posts with label research. Show all posts

Ayurveda medicine for Swine Flu- Research result

Thursday, January 28, 2010

Chennai-based RRF launches Ayurveda remedy for swine flu 'Ayusrem'
Thursday, January 28, 2010 08:00 IST
Peethaambaran Kunnathoor, Chennai


The Food & Drug Administration (FDA) in the Union Territory of Pondicherry has granted licence to Chennai-based Ramoni Research Foundation (RRF), an institute conducting research in Ayurveda medicines, to manufacture and market an Ayurvedic antiviral medication Ayusrem, which is a potential drug to prevent and treat H1N1.

The scientists at the foundation claimed that the drug is a potential choice to prevent and treat H1N1 flu and will prove to be a boon to the people as it is being launched at a time when the entire world is stepping up efforts to tackle the H1N1 pandemic. According to the scientists, the drug is made of extracts from anti-viral plants and antipyretic plants like Andrographis paniculata, Curcuma Longa and Vetiveria zizanioides. Extracts of Immunomodulant plants like Zingiber officinale and Piper nigrum have also been included. The Analgesic ingredients in the formulation are from Andrographis paniculata, Zingiber officinale and Cyperus rotundus.

Claiming that the herbal product can contain the spread of swine flu and other strains of viruses, RRF has written to the Department of Ayush to take measures to evaluate the effect of medicinal plants and formulations for antiviral activity. The letter says that the potential of medicinal plants is well known for their antiviral activity and the Herbal Sciences Department of the Madras University has initiated several studies on it. The Centre has generated scientific data on 130 plants so far, which will help millions of sufferers of virus diseases, the scientists told Pharmabiz.

The foundation hopes that the permission by the US FDA will reap results in a way that it will help RRF to penetrate into the huge Indian Ayurvedic market and the growing global market of Ayurvedic products when viral diseases are spreading alarmingly and taking lives across the world. RRF’s Ayusrem is the outcome of a joint venture with the Herbal Science Research Centre of Madras University.


The scientists in the foundation said US FDA in Pondicherry is the first regulatory authority to certify and approve the drug for sales after its invention by Chennai based institutes six months ago. The inventors of the remedy have claimed that within this short span of time, the medicine could cure various kinds of viral diseases of about 2000 people including those affected with A H1N1 viruses.

RRF has invented the medicine Ayusrem, after years of researches associating with the Centre for Herbal Sciences at the University of Madras. When the drug was launched in September last year, it was a formulation of Ayurveda and Siddha preparations. Later, the formulation was completely restricted in Ayurvedic method only, said the inventors of the product, Dr K Balasubrahmaniam and professor Dr A Raaman.

Last week, in a function organized in Pondicherry Lt Governor Dr Iqbal Singh inaugurated the official launching of the medicine by handing over a strip of 10 tablets of Ayusrem to the Health & Family Welfare Minister E Valasaraj. Public health minister A Namasivayam was also present on the occasion.

After the invention of Ayusrem, Ramoni Research Foundation has bagged three Awards of Excellence. National Citizen Excellence Award from Intellectual People and Economic Growth Association, New Delhi for Outstanding Contribution, International Achievers Award for invention of Ayusrem by International Achievers Forum, Thailand, and Bharath Gaurav Award from India International Friendship Society for meritorious services.

D Balasubrahmaniam, the chairman of the foundation said RRF has signed an agreement with Pondicherry based Dr Milton’s Laboratories to manufacture the drug and inked another contract with Chennai-based Berjayaa Marketing Private Ltd for domestic marketing. They have also signed certain pacts with Leonex Systems of Malaysia to market the Ayurvedic antiviral remedy.

Source: PhamaBiz

Ayurvedic bhasma oldest form of nanotechnology: BARC prof

Sunday, December 20, 2009

TNN 14 December 2009, 11:11pm IST

SURAT: The bhasmas' used in Ayurveda for treatment of various diseases for the past several centuries is the oldest form of nanotechnology, said head of solid state chemistry section at Bhabha Atomic Research Centre (BARC), Mumbai, Prof AK Tyagi.

Tyagi was in the city to take part in a one-day seminar on Nanotechnology and its application' at department of chemistry in Veer Narmad South Gujarat University (VNSGU).


"We are preparing to use it again for various purposes," Tyagi said. The seminar was organized with funds given to the department of chemistry by University Grants Commission (UGC) under special assistance programme. The department is also awarded five research scholarships.

Apart from Tyagi, Dr PA Hassan, Dr V Sudarshan and Dr Dimple Dutta, all from BARC, participated in the seminar and delivered lectures.

In his lecture Tyagi said the nano particles are 1 crore times smaller than a hair and due to its small size, the basic characteristics also get changed. Due to change in electrical, thermal, magnetic, optical, chemical and biological characteristics, the particles can be used for various products. Use of nanotechnology has already been started in food technology and medical technology. Research is on across the globe for use of technology in robotics and at advance level of health facilities. Gradually, the technology will become part of routine life of human beings, he added.

VNSGU vice-chancellor BA Prajapati, head of chemistry department P Bahadur and faculty member KC Patel were also present at the event.

Source: Times of India

Relevance of Ayurvedic Holism- by Dr. B.M.Hegde

Tuesday, November 3, 2009

Absence of evidence Vs Evidence of absence


By Dr. B. M. Hegde, India [ Published Date: November 2, 2009 ]

“I am easily satisfied with the very best.” – Winston Churchill
It took nearly fifteen hundred years for the medical community to realize that Galen’s hypothesis of the blood circulating from the liver, propounded in 127AD, was wrong. It was in the 17th Century, William Harvey wrote his de Motu Cordis. (1628 AD) In the field of astronomy it took five Centuries for scientists to realize the folly of Ptolemy’s hypothesis that the sun goes round the earth. Copernicus, in the 7th Century, came on the scene to show that the earth, in fact, goes round the sun! Reductionist science that we follow in medical research does not work in the dynamic human system. Still we hang on to it despite evidence to the contrary as it has become a lucrative trillion dollar business. We presume, wrongly though, that the absence of evidence is the same as evidence of absence. Therefore, we refuse to accept anything that defies the reductionist statistical deductions. Evidence based medicine today has become evidence burdened instead.


Although I have been pointing this out time and again for the last four decades, medical scientists never took me seriously. The movement gained respectability when once the Institute of Medicine report in the US clearly showed medical interventions in the hospitals as the third important cause of death next only to heart attacks and cancer and the Adverse Drug Reactions as the fourth cause. (JAMA 2000; 284: 483-485) Now there is a world wide movement for establishing the right science in medicine of Whole Person Healing. This was practiced for “times out of mind” in the ancient healing systems of Ayurveda. Newer scientific methods have been able to establish the validity of many other complementary systems of medicine like homeopathy, naturopathy, Siddha, energy medicines, faith healing, reiki, Qi gong, acupuncture, and fast wound healing methods of India and the Sufi saints, reconstituted water therapy et cetera.

The leader of the movement in the US, Professor Rustum Roy, the father of nano-science (not nanotechnology), a scientist of great repute, who had been nominated for the Nobel several times in the past. He, in his early 80s, is still the Evan Pugh professor of Solid State Emeritus at the Penn State University! Nano-science was born when, in the early 50s, Prof. Roy invented the sol-gel technique to extract nano-particles. Even now scientists in the field of nano-science use the same method. His paper on Sol-Gel technique is cited 65,000 times to date, a record of sorts! Interestingly, Prof. Roy is more interested in the Giga problems of mankind all over the world like poverty, hunger, ignorance and illnesses. He is using his scientific clout to help the poorest of the poor using his research acumen to solve those Giga problems.

Manufacturing molecules by altering the atoms is the basis of nano-science. One could make diamonds from coal and semi-conductor chips from sand. Having realized the futility of reductionist science in medicine Prof. Roy took upon himself the arduous task of scientifically validating the multitude of complementary systems of medicine personally using his rigorous scientific methods of scrutiny. Only those that passed his tests were included in the WPH movement.

His great faith in Ayurveda as the mother of all medical wisdoms made him to coax the Indian Council of Scientific and Industrial Research to organize a preliminary workshop on WHP in New Delhi some time ago. More meetings in the US followed the Delhi meet. One such was the first ever International conference on WPH for four full days at Tai Sophia Institute in Laurel, Maryland. Let us see how WPH works. In contrast to reductionism of organ based specialties, the science of Ayurveda, for example, takes into consideration the mind, body, spirit and the genome into consideration while treating patients. Ayurveda believes that all illnesses are born in the mind and grow in the body with the influence of the genes in a conducive atmosphere. For the healer it is not as important to know what disease one gets, as it is to know who gets a disease. The latter would answer the vital question that had been dogging positive sciences for ages, the answer to the question “why?”. Positive sciences could, at best, answer “how” or “how much” but not “why?” A conventional physiologist could answer how does the heart contract but not the question as to why does the heart contract? Space constraints do not permit me to go deep into the great science of Ayurveda.

Rustum Roy’s work on the structure of water (not chemistry: he is basically a chemist, though) opened the flood gates for homeopathy research. When a homeopathic drug is diluted in water thousands of times the final water might not contain any chemical entities of the drug but the drug would leave its foot prints in water by changing the structure of water. Reductionist science of water would have to be a combination of H2 and O. Both these atoms are volatile but water, a combination of the two, is far from volatile. This is the bane of reductionist science of medicine where we study a cell or an organ and project it on to the man and predict the unpredictable. This has led us to this sorry state of affairs where medicine has become a bane to society instead of the boon that it ought to be. Many scientific studies have shown the good effects of homeopathic medicines.

Hormesis, another new concept developed by Edward Calabrese, has shown how most drugs have a beneficial bio-positive effect on the body in very small doses while the same drug in larger doses (that we give in therapeutics based on the pharmacodynamic studies of reductionism) would be bio-negative. He showed it elegantly in vitamin C. Whereas the small dose of vitamin C in a tomato is bio-positive, the larger therapeutic dose, in the long run, would damage the system. It is also possible that there are hitherto unknown entities in the tomato that prevent the vitamin C to manifest its bio-negativity. This gives credence to the holistic science of Ayurveda also.

Qi gong, reiki, and even faith healing depend on the movement of bio-energy, the leptons of quantum physics, from the healer to the patient. The consciousness of the healer is as important as the vehicle that the healer uses (say a drug). Similarly, the consciousness of the patient should be more important in the final healing process. This was demonstrated by a psychiatrist from Stanford offering himself as the patient to study the quick wound healing methods of the Sufi saints in Iraq. He demonstrated that during the conference. Our own paper on Heart Rate Variability, using the latest computer two dimensional imagery and the wavelet quotient analysis, showed the principle of “mode-locking” (Edward Laurenz’s hypothesis) where organs work in tandem and not in isolation. Even the age old Placebo effect has now been scientifically shown to exist with chemical changes in the brain that could be proved by blocking the chemicals using naloxone to nullify the placebo effect.

The studies published in the leading medical journals on the power of intercessory prayer in the management of myocardial infarction does work on the principles of bio-energy transfer. In depth study of the brain by David Shannonoff Khalsa, professor of Neurobiology in San Diego, revealed extensive changes that took place in the brain during meditation. His published works on Kundalini Yoga in the management of intractable diseases like obsessive compulsive disorders, anxiety states, and epilepsy are an eye opener. There is now ample evidence that the whole person healing is the future of modern medicine.

Scientific enquiry into the claims of any system of healing should be the way forward. There should be no compromise about validating the claims of all the complementary systems. The scientist’s job is to take the wheat from the chaff and put together a new system of medical care delivery, the future modern medicine, called meta-medicine, wherein the best in all those systems are incorporated without bias. David Eddy, a cardiovascular surgeon at the Stanford in the past, had already shown the role of non-linear mathematics of chaos and fractals and holism in human physiology. (www.archimedesmodel.com) Modern medicine’s quick fixes are useful in emergency care although some of those methods have not been fully authenticated. For the majority of patients in the non-emergency set up the integrated system that is conceived above would bring down the cost of medical care significantly. This would make medical care reach the unreached. This would also bring down the incidence of ADR, the fourth cause of death these days in our hospitals. Let this new system do most good to most people most of the time.

We have started the World Academy of Authentic Healing Sciences in Mangalore, with the blessings of our parent body, the Friends of Health, headed by Rustum Roy at Penn. State University, continuing the good work that the latter does in the US. We have made considerable progress in the last couple of years wherein we have authenticated many new methods of easy cure for so many hitherto difficult-to-treat ailments. We have also started a new journal, Journal of the Science of Healing Outcomes, in its second year, publishing scientific studies after due super peer review by eminent scientists, including Nobel Laureates, who are on our editorial board.

Rustum Roy is the co editor in chief of JSHO (www.thejsho.com) with me as the editor in chief. We also have another centre for research in Chennai under the able leadership of Professor CV Krishna swami, where our friends have donated money to build our own research building. All our efforts have to be funded by well meaning philanthropes since we do not accept funds from the pharmaceutical and/or medical devices industries! Hope we will be able to put together a new system of inexpensive medical care that would be a boon to the common man. Absence of evidence is not, therefore, synonymous with evidence of absence.

“The means by which we live have outdistanced the ends for which we live. Our scientific power has outrun our spiritual powers. We have guided missiles and misguided men.” — Martin Luther King Jr.
Dr. B. M. Hegde MD, FRCP, FRCPE, FRCPG, FRCPI, FACC, FAMS, is editor-in-chief of The Journal of the Science of Healing Outcomes; chairman, State Health Society’s Expert Committee, Govt. of Bihar, India, Visiting Prof. Cardiology at The Middlesex Hospital Medical School – University of London, Affiliate Prof. of Human Health – Northern Colorado University, Visiting Prof. Indian Institute of Advanced Studies – Shimla, Retd. Vice Chancellor, MAHE University – Manipal. Prof Hedge regularly gives talks on AIR, Doordarshan, BBC and Zee TV, London.

Source: Mangalorean.com

Research Confirms Healing Effects of Herb Terminalia Chebula

Saturday, October 3, 2009


The Terminalia Chebula known as Haritaki is an age old Indian Herb. Its medicinal benefits are many. Research now confirms the healing properties of this herb. This article shares the findings of the research study and lists the home remedial benefits of this herb.

Knowledge Gained about Terminalia Chebula from Research:

•Extracts from the leaves of this herb were applied on the wounds of experimental rats.

•The wounds contracted at an improved rates.

•There was regrowth of skin over the wounds in short time.

•Collagen is an important component with which tissues are made.

•The Study found that the Collagen content in the tissues was high because of this herb.

•There was 40% rise in the strength of the tissues.

•Researchers believe that Antioxidants are present in this herb.

•These antioxidants are responsible for the healing properties of this herb.

•The Study also confirmed the antiseptic qualities of the herb.

•The fruits of this herb are dried and made in to fine powder.

•Intake of 3-5 gms of the powder per day provides the benefits of this herb.

•Its intake leads to no side effects.

Health Benefits of Terminalia Chebula:Ayurveda prescribes this herb in curing swellings, skin and eye diseases. It can be used as home remedy against fevers, cough, asthma and urinary diseases. Its antibiotic qualities can provide strength to the body to fight against swine flu. It is known for its proven ability to remove stagnant stool in the intestine. This herb has the ability to stop bleeding and prevent a medical condition called Hemorrhage.

Source: YgoY.com

Researches Prove Ayurveda Again- Moringa Leaves for Health

Sunday, September 6, 2009

NRDC ready to launch Moringa leaf powder as nutraceutical, scouts for commercialisation

Saturday, September 05, 2009 08:00 IST
Nandita Vijay, Bangalore

National Research Development Corporation (NRDC) is now ready with its research findings on Moringa or drum stick leaves powder proving to have high anti-inflammatory, antispasmodic and diuretic properties.

The main research was carried out by a team at Tamil Nadu University. NRDC has been approached for commercialisation of the product for which it is on the look out for potential Indian herbal manufacturers.

Moringa contains properties which help rheumatism, arthritis and other joint disorders. It is also recommended as cardiac and circulatory stimulant. Biological studies have confirmed that the drum stick leaf has anti-inflammatory, antispasmodic and diuretic activities.

Many herbal manufacturers in India are already engaged in exporting Moringa leaves powder as a nutraceutical and in oil form. According to the research findings by Tamil Nadu University, the Moringa leaves can be filled in capsules. "Moringa is the Tree of Life. Doctors use it to treat diabetes in West Africa and high blood pressure in India. We have looked at developing the pure form of the powder which is natural and safe", said HK Phanikumar, consultant, business development, NRDC.

According to the Tamil Nadu University researchers, capsules formulated with Moringa leaves can be certified to prove that there are no additives. Referring to the ancient texts of Ayurveda, the researchers have proved that the Moringa powder helps to boost energy and provides the required nutrition besides rebuild weak bones, enrich anaemic blood. It has calcium content of equivalent to 4 glasses of milk, the vitamin C of 7 oranges, and the potassium of 3 bananas.

Further daily consumption of the Moringa leaf powder which is high in Vitamin A can shield against eye disease, skin disease, heart ailments, diarrhoea among others. Its vitamin C content helps in preventing colds and flu. Its high calcium content is good for strong teeth and prevention of osteoporosis. Being a source of potassium and proteins it is recommended brain and nerves functions.

The competitive advantage of the leaf is that compared to common foods, its values per 100gm. edible portion is vitamin A 6780 mcg and carrots: 1890 mcg vitamin C 220 mg and oranges: 30 mg. Calcium 440 mg and cow's milk: 120 mg. Potassium 259 mg and bananas: 88 mg. Protein 6.7 gm cow's milk: 3.2 gm.

There are several research institutes which have worked on process development of Moringa leaf. Efforts are also on to bring out value-added products to the market.

According to Phanikumar, the product is apt for Indian small and medium manufacturers of herbal products as it can be produced on large scale. With the current high level of awareness about the Moringa leaf nutrition in the market, companies can capitalise on the revenues generation opportunities not only in the domestic market but the international arena, he added.

Source: PhamaBiz

38 ayurvedic formulations identified for 8 disease conditions

Thursday, September 3, 2009

38 ayurvedic formulations identified for 8 disease conditions under Golden Triangle scheme

Thursday, September 03, 2009 08:00 IST
Joseph Alexander, New Delhi

As many as 38 ayurvedic formulations have been identified for eight disease conditions and 20 of them have been provided to CSIR for pre-clinical studies so far under the Golden Triangle Partnership scheme set up for validation of traditional ayurvedic drugs and development of new drugs.

The CSIR has submitted the status report of 10 formulations. They are tagradi kwatha (insomnia), medhya (ADHD), ashwagandha churna (anxiety neurosis), haritkyadi churna (dyslipidemia), GTP-HN-1 (hyper tension), brahmi ghrita (ADHD), gokshuradi guggulu (BPH), lakshadi guggulu (osteoporosis), nirgundi tail (joint disorders) and singhanada guggulu (joint disorders).The pre-clinical studies of all other formulations were under progress in different institutions now, sources in the Ayush department said.

The scheme was set up as an integrated technology mission for scientific validation of traditional medicines for identified disease conditions for which the apex organizations like Department of Ayush, Central Council for Research in Ayurveda and Siddha, CSIR and ICMR have joined hands. The objective of the scheme is to bring safe, effective and standard Ayurveda, Siddha, Homoeopathy and Unani products and develop new drugs of national and global importance. The apex bodies also collaborate with other institutions and companies with this purpose.

"The project is going well and more new collaborations are in the offing. The idea is to bridge the gap between modern medicine and traditional medicine so that India can tap the vast potential in the arena. It is the triangle being built between modern science, modern medicine and traditional medicine, giving a golden opportunity to the country," an official explained.

The CCRAS has also collected the inputs for protocols of different diseases and submitted to the ICMR for further revision. The draft protocols of hypertension, dyslipidemia, HIV/AIDS, osteoporosis and rheumatoid arthritis were thus given to the ICMR.

Source: PharmaBiz

AYUSH dept validating ayurvedic drugs developed by private institutions to treat cancer

Thursday, August 6, 2009

Wednesday, August 05, 2009 08:00 IST
Joseph Alexander, New Delhi

Many ayurvedic plants including turmeric, semicarpus anacardium, and tinospora cordifolia have shown anti-cancer properties in the recent studies conducted by the government institutions. The government is now in the process of validating some anti-cancer drugs developed by private institutions through clinical trials.

Clinical studies have been done under different projects by the Union Ministry of Health to assess the use of ayurvedic treatment in different types of cancer. A pilot project was sanctioned by the ministry to study the effects of metal based formulations prepared by Vaidya Balendu Prakash of Dehradun in the treatment of acute pro-myllotic leukaemia (APML) in 90 days. As many as 15 patients were enrolled in the study out of which 10 patients had shown a complete remission in peripheral blood smear, sources said.

In another effort to develop ayurvedic drug for cancer, clinical trials of 'Ayush QOL - 2C' developed by Central Council for Research in Ayurveda and Siddha (CCRAS) for improvement of quality of life of those receiving chemotherapy/radio-therapy, have been initiated at St Johns medical college, Bangalore and at the All India Institute of Medical Science, New Delhi.

"The government is ready to promote any research initiative taken up by the private doctors or institutions, along with research by government bodies. The goal is to have cheaper and effective drugs to treat cancer. All projects are in progress, but it will take some more years to officially introduce a drug with government approval after all validations," an official of the Ayush department said.

On the request of Nand Lal Tiwari of Jaipur, the CCRAS has undertaken the study of anti-cancerous property of herbal compounds 'Carctol' to ascertain the claim. Similarly, a claim made by Krishn Gopal Ayurved Bhavan, Dharmartha Trust, in Rajasthan on their proprietary drug 'Cancer Gaza Kesari' has been subjected to pre-clinical safety studies by CCRAS, he said.

Source: Pharmabiz